Yes. It's extremely easy, in fact, and as usual with Photoshop there are several ways to do it. The simplest, non-destructive approach is to add a Black & White adjustment layer and clip it to the image layer.
Use the "scrubby" tool to darken or lighten areas as needed to get the B&W conversion you're looking for. You'll see the color sliders in the adjustment panel move as you do this, and you can move them individually yourself. To get that very dark skin effect, start with the High-Contrast Blue filter setting, and improvise from there.
If you then want to have some areas of color (the lips and the pink dot in your example), paint them in using a black brush, or select and fill with black, in the layer mask that is automatically added to the adjustment layer by Photoshop.
took about 5 minutes, using exactly the above technique. Because it's all done with an adjustment layer, nothing in the original image has been changed, and it's easy to change any time later.