New answers tagged snapping
Create a rectangle that surrounds the area where you want the guides. Select rectangle and go to Object -> Path -> Split Into Grid ... Set 80px for width and height and click OK. Go to View -> Guides -> Make Guides
Change the Snapping Tolerance in the Preferences. But honestly if 2 pixels is too large a distance, you should be zoomed in viewing the pixel grid, because the only smaller increment is 1 pixel which the pixel grid handles.
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