New answers tagged sprite
Actually I found this gem http://spritepad.wearekiss.com/ I'm able to save SpritePads and keep adding to them as I need to. The UX on this is a bit lacking (IMO) but it saved me so much time it was ridiculous.
The answer to your dreams managing sprites with Sass and Compass. Compass makes it very easy to combine multiple images into a sprite and then manage them as the project goes on. Here is another tutorial with more examples: Web Design: CSS Image Sprite With Compass
If this were my issue, I'd configure a photoshop file with guides where I needed them and everything positioned correctly. Then I could edit anything, everything remains within the guides I've configured, and I could add new items at anytime. Then simply re-save the file via Save for Web as a .png (or whatever) and have a new sprite sheet without anything ...
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