bigger, bolder == more noticeable, more legible.
ALLCAPS == shouting & actually harder to read.
I sometimes use title case on mine, TxxxxxMedia, which makes it slightly easier to read & my mail server doesn't mind it.
Late edit
ymmvAccording to the other, later, answers here, no server should mind any type of case differentiation in the domain name, only potentially in the part before the @, so camelCase or TitleCase is fine.