I am doing my resume right now, and I have a lot of acronyms. I'm using an OpenType font, so I've always put those acronyms in small caps. I've never quite been sure what to do, though, when a heading line or a list item begins with an acronym. When it begins with any other word, I would capitalize that first word. But with an acronym that's set in small caps, do I bump the first letter up to regular caps? Looks weird, to my eye.
Small caps alone
Small caps with full caps