When formatting in Chinese text, I 'm wondering if you can create a paragraph style so the Chinese is set in 1 Chinese font, while the numbers are set in English font. So you don't need to highlight and change each number individually in the English font when applying different styles.
If i understand correctly, you have some CN text content which includes some numbers which you need to typeset in another font. In which case you need to create a GREP style linked inside your CN paragraph style, to apply this other font for all the numbers. This, assuming your are using InDesign.
In InDesign, set the base Paragraph Style as you want, then use Character Style to swap the font of the desired characters.