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How can I get rid of this odd overlay? It's currently highlighted in blue ... I've tried clicking on all sorts of buttons but could not shake it off.
Those are safe regions of your camera: Blender has the same tinted border. If you don't want it when looking through the camera, you can go to Options > Configure > View > Tinted Border and disable it.
Options > Configure > View > Tinted Border
View Settings (shift+v) > View > Safe Frames
Required, but never shown