I used QuarkXpress years ago when freelancing on a temporary basis with a local printer/publisher, when I edited manuscripts for local authors and developed the layouts. The version with which I am familiar is Quark 4.1. (A long time ago!)
But I am now considering returning to editing and publishing manuscripts, so which is preferable please: QuarkXpress or InDesign? I have a 64-bit PC running Windows 10.
I have little to no experience of Adobe as I have never used PhotoShop, as I used the software provided by marketing departments at the time, such as PaintShop Pro.