The better question is: "Is it worth it?" which I would argue is, in almost all cases, a resounding no.
It simply is not that usable. Google's 20thingsIlearned (the first example I gave) is really cool and well done, but it takes a while to read all of the content, is pretty heavy on performance, and isn't responsive. Implementing this would remove two of the unique characteristics of the web - fitting content to the device and working across all platforms.
It also takes a good bit of work. Even going off of these examples and using their setup it'll likely still take you longer than you want to spend on it. They will only be effective if they're very very high quality, which even most of the examples I shared do not do. That's nothing against your skill, just statement of fact.
What I recommend instead is to create an awesome experience in other ways. Focus on the design and user flow and make sure you're conveying exactly the message you want to through each little detail. Find other ways to have interaction between users and your site, especially looking at how other people do it. UserFlowPatterns is a great place to get some ideas.