In commercial printing, the important factor is Ink Limits. In many cases, no part of a print piece can surpass 300% ink limits. What that means is you add up the % of each ink to determine the total coverage.
This is just a sample to show the theory since what you posted is an RGB image and all I can do is convert it to CMYK here (Based on my color settings)... but if you look at the Info Panel in Photoshop you can hover your cursor over areas to see the percentages:
So for the dark area the cursor is over, 245%. I'd move my cursor around a bit more to the darker areas to verify the percentages are all relatively close.
If you aren't pushing 300% then you won't have an issue.
Also be aware that Color Settings within Photoshop look out for this for you. If your Color Settings for CMYK images is set to "US Web Coated (SWOP)" then Photoshop itself won't allow color builds to go beyond 300% by default.
In most cases a heavily saturated CMYK image is not an issue as long as you are within ink limits. Sometimes it can take a better quality print provider if you are doing things like this across entire pages. It takes some pressman skill to maintain high coverage across a page. For spot photos here or there, there shouldn't really be an issue.
If you are overly concerned about color matching, a ChromaKey or color proof is imperative (not a PDF proof).