I have been experimenting with exporting images from Lightroom 6 using a variety of rgb and cmyk profiles as both jpegs and tif (8bit and 16 bit). The images all look much the same on Windows Explorer but when I place an image that uses proPhotoRGB profile into inDesign there is an extensive change in the predominant colour (Blue). I get the same problem regardless of whether I use jpg, 8bit tiff or 16bit tif. The problem only occurs when you place the image the colours for all versions look the same when selecting the image from a dialog
The image below shows how the images all look the same in the open dialog but when the image placed into the document it looks different.