And here is an oposed opinion.
I have an Intuos 5 now, This is my second tablet, which I almost never use. I use a good quality mouse.
On my first tablet I reduced the workable area to about 3x2 inches, so I only moved my wrist. I have not done this on the intuos.
Regarding the hand-eye cordination you will have no problem, it is the same as using a mouse.
The reason I do not use it as much is because it is too sensitive for vector based drawing, the small movement you need to push the pen down moves my cursor position. But for retouching photos or for painting it is way far better than using a mouse.
The diference between the basic wacom to some more advanced models is that the first ones do not sense the pen inclination, but that is not that important feature.
Other features are that you have controls on the tablet, but that can be a drawback if you do not have space on your desk, and you use a lot the keyboard, you probably do not need thoose extra controls.
And another is that some are aware of hand geastures, like a tablet, to zoom and rotate the canvas, but not all aplications can rotate the canvas.