If you do not have experience on printing process or costs you should probably send just 1 copy of the design with bleed and leave the printer to arrange the copies.
But this depends. If you are sending to a copy shop, where there are no design personal, and you just need some few copies, you need to prepare your page. The size is limited to the one the printer can handle. Probably Letter or Tabloid if you are using imperial units.
You need to know the exact paper size, the necessary margins where the paper can not be printed, and leave some gap between the pieces to cut them.
If your business card measures, for example, 90x50mm prepare one pdf with a few millimeters for bleeding, 3 mm each side so your document is 101x61 mm. Sorry about using the metric system.
But the truth is... ask the printer where you are going to send your files.