I just recently upgraded to Photoshop CS6, and so far, I've run into a major issue regarding my workflow. In CS5, I was able to have an image snap to an intersection of guides (in this case, the center of the image); while I can do that in CS6, it doesn't seem to allow me to center an object if the object is not of a certain size.
I can't think of a way to explain this, so, I've attached two pictures--one in CS5 and the other in CS6. I'm in the process of transforming an object in the program in each shot. It is the same file, with no modifications to it. You'll notice in CS5 that the x/y coordinates are (50px, 50px)--the canvas is 100x100 pixels; while in CS6, the x/y coordinates are (50.50px, 50.50px). Even if I manually input (50px, 50px) in CS6, press "Accept", and I transform the object again, the coordinates will have not changed (they still read (50.50px, 50.50px). Also, you can see that in CS5, the anchor is highlighted in red (as to indicate it is centered on the intersection)--whereas in CS6, this behavior is absent.
Is this how this is supposed to be? It's incredibly frustrating. If I made the object I'm trying to center either a few pixels larger or smaller, it will allow me to perfectly center it. Not sure why that is, but CS5 doesn't make me do that.